Behavioral Neuroscience of Drug Addiction by David W. Self
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About Behavioral Neuroscience of Drug Addiction by David W. Self
Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal deviation. The disorder affects millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates and that chronic drug use causes aberrant alterations in these rewa- processing systems.
Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as the exaggerated, altered, or dysfunctional expression of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural defcits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer Series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience
- ASIN: B008CLU62G
- Publisher: Springer; 2010th edition (December 18, 2009)
- Publication date: December 18, 2009
- Language:: English
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