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Zoloft – Usages, Side effects, Risk factors, Precautions
Here in this post, we are discussing the “Zoloft”. You can read usages, side effects, Risk factors, and warning information. Keep visiting Psychology Roots.
About Zoloft – Usages, Side effects, Risk factors, Precautions
Zoloft is available in the following dose
- 25mg
- 50mg
- 100m
Zoloft
Disorders treat through Zoloft
Zoloft is used for the following disorders:
- Social Anxiety Disorder
- Major Depressive Disorder
- Panic Disorder & Post Traumatic Stress Disorder
- Obsessive-Compulsive Disorder
- Pruritus
- Premenstrual Dysphoric Disorder
Dose according to age groups
For adults
Social Anxiety Disorder
Initially, 25 mg orally per day is administered. It may increase by 25 mg in 1 week. It may not exceed 200 mg per day.
Initially, 50 mg orally per day is administered. It may increase by 25mg in 1 week. It may not exceed 200mg per day.
Panic Disorder, Posttraumatic Stress Disorder
Initially, 25 mg orally per day is administered. It may increase by 25mg in 1 week. It may not exceed 200 mg per day.
Initially, 50 mg orally per day is administered. It may increase by 25 mg in 1 week. Do not exceed 200mg per day.
Premenstrual Dysphoric Disorder
Throughout the menstrual cycle Initially 50 mg per day orally continuously administered or administered during the luteal phase only at the onset of every new menstrual cycle, it may increase by 50. When it is continuously administered it may not exceed more than 150 mg per day. During the luteal phase, it may not exceed 100 mg per day.
For children
Zoloft is not safe and effective for <6 years old children.
For 6-12 years
Initially, 25 mg per day orally is administered. It may increase by 50mg per day at 1 week Do not exceed more than than 200 mg per day; give qHS if somnolence experienced.
Pruritus (Off-label)
For 5 years children, 25-100 mg daily is administered. The effective dose is 75-100md.
For older age
The elders are more exposed to SSRI/SNRI-induced hyponatremia. They should be monitored carefully.
Initially, 25 mg orally per day is administered. Every 2 to 3 days it may increase by 25 mg. Do not exceed 200mg per day.
Alzheimer /dementia-related depression:
Initially started with 12.5 mg per day and titrated every 1 to 2 weeks to respond. It may not exceed 150-200 mg.
Side effects of Zoloft
Following are the side effects of Zoloft
- Ejaculation disorder
- Diarrhea
- Insomnia
- Nausea
- Fatigue
- Headache
- Dizziness
- Agitation
- Dry mouth
- Anxiety
- Drowsiness
- Anorexia
- Impotence
- Constipation
- Vomiting
- Paresthesia
- Pain
- Sweating
- Back pain
- Malaise
- Chest pain
- Increased appetite
- Asthenia
- Palpitations
- Hypoesthesia
- Rhinitis
- Weight gain
- Myalgia
- Tinnitus
- Yawning
Black box warning
According to the studies, antidepressants may cause an increased risk of suicidal thinking and behavior in children, adolescents, and young adults (<24 years) who are taking antidepressants because of their illness. Over the24 years of age suicidal thinking did not increase. In adults, over 65 years of age suicidal thinking was slightly decreased.
When given antidepressants to young adults and children risks should be considered against the benefits. Any change in behavior and suicidal ideations should be carefully monitored. It should be monitored for initially 1 to 2 months of administration of Zoloft. The family should inform the health care provider immediately if they see any unusual behavior.
Zoloft is not approved for pediatric bipolar and major depressive disorder.
Cautions
Suicidal ideation and clinical side effects may occur despite medications.
- Carefully used for the patient having a seizure disorder.
- Mania symptoms or precipitate mania become worse in patients having a history of bipolar disorder.
- The risk of hyponatremia and cognitive/motor functions impairment may increase in the elders.
- The risk of bleeding increase in patients taking
- Anticoagulants/antiplatelets.
Pregnancy:
The evidence related to SSRIs during pregnancy is conflicting and the risk of persistent pulmonary hypertension in newborns is increasing.
In Neonates following complications are present who are exposed to SNRIs/SSRIs in late third-trimester
- respiratory problems.
- irritability
- feeding difficulties
Avoid abrupt withdrawal
Due to antidepressants, therapy bone fractures are caused. the patient might have bone pain, tenderness, and brushing. Consider these possibilities. Medicine should not be avoided abruptly.
Pregnancy
Use of Zoloft in the third trimester causes complications in newborns and may need to be hospitalized for a longer period of time and need respiratory support, and tube feeding.
Persistent pulmonary hypertension of the newborn
Newborns have a risk of persistent pulmonary hypertension (PPHN) if Zoloft is used during pregnancy.
Lactation
Zoloft is distributed into milk.
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